The duration of effectiveness for a 60mg dose of dapoxetine, the active ingredient in Priligy, can vary depending on individual factors but typically ranges from four to six hours. As a medication designed to treat premature ejaculation, dapoxetine works by increasing serotonin levels in the brain, which helps delay the ejaculatory reflex and prolong the time before orgasm. When taken orally approximately one to three hours before planned sexual activity, the 60mg dose reaches its peak concentration in the bloodstream, providing the maximum therapeutic benefit during this window. Clinical studies have shown that at this dosage level, men experience a significant increase in intravaginal ejaculatory latency time compared to a placebo. It's worth noting that dapoxetine has a relatively short half-life, meaning its effects begin to diminish after a few hours as the drug is metabolized and eliminated from the body. Factors such as age, metabolism, and individual response can influence the exact duration of action, so it's essential to follow the prescribed dosing schedule and consult a healthcare professional for personalized guidance.
